Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304100 | 0.90 | MRGPRX4 (0.42) | SCN9AGABRG2GABRB3GABRA3MAPT | |
| SCHEMBL8300795 | 0.81 | NR1H2 (0.40) | NR1H2NR1H3HSD17B2MAPTSMN1; SMN2 | |
| SCHEMBL8304787 | 0.81 | MAPT (0.41) | MAPTSMN1; SMN2 | |
| SCHEMBL8298660 | 0.81 | MAPT (0.43) | NR1H2NR1H3KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL8304674 | 0.81 | GABRA5 (0.38) | MAPTORAI1 | |
| SCHEMBL8304720 | 0.80 | CYP1A2 (0.38) | NR1H2NR1H3SCN9AHSD17B2MAPT | |
| SCHEMBL8298161 | 0.80 | HSD17B2 (0.39) | NR1H2NR1H3HSD17B2MAPTSMN1; SMN2 | |
| SCHEMBL8300261 | 0.80 | NR1H2 (0.39) | NR1H2NR1H3HSD17B2MAPTSMN1; SMN2 | |
| SCHEMBL8300752 | 0.80 | KDM4E (0.38) | MAPT | |
| SCHEMBL8300094 | 0.80 | MRGPRX4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648752-B1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |