Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309181 | 0.99 | MAOB (0.51) | MAOBMAOAL3MBTL1CYP1B1ABCB1 | |
| SCHEMBL8309109 | 0.97 | MAOB (0.54) | MAOBMAOAL3MBTL1CYP1B1ABCB1 | |
| SCHEMBL8309100 | 0.94 | L3MBTL1 (0.49) | MAOBMAOAL3MBTL1CYP1B1ABCB1 | |
| SCHEMBL8304325 | 0.93 | CYP1B1 (0.54) | MAOBMAOACYP1B1MEN1KMT2A | |
| SCHEMBL8429312 | 0.90 | POLB (0.52) | MAOBMAOACYP1B1PPARGCYP1A2 | |
| SCHEMBL8309092 | 0.90 | ABCB1 (0.52) | MAOBMAOAL3MBTL1CYP1B1ABCB1 | |
| SCHEMBL8305144 | 0.88 | L3MBTL1 (0.60) | L3MBTL1CYP1B1ABCB1MEN1KMT2A | |
| SCHEMBL8305061 | 0.87 | CYP1B1 (0.59) | MAOBMAOACYP1B1MEN1KMT2A | |
| SCHEMBL8309259 | 0.86 | CYP1B1 (0.56) | L3MBTL1CYP1B1ABCB1MEN1KMT2A | |
| SCHEMBL8309183 | 0.86 | MAOB (0.51) | MAOBMAOAL3MBTL1CYP1B1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |