Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309100 | 0.95 | L3MBTL1 (0.49) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8306264 | 0.93 | CYP1B1 (0.63) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8309109 | 0.92 | MAOB (0.54) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8309181 | 0.90 | MAOB (0.51) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8305061 | 0.90 | CYP1B1 (0.59) | CYP1B1MEN1KMT2ATP53CYP1A1 | |
| SCHEMBL8305144 | 0.90 | L3MBTL1 (0.60) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8305537 | 0.90 | MAOB (0.51) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8309259 | 0.89 | CYP1B1 (0.56) | ABCB1CYP1B1MEN1KMT2ACYP1A1 | |
| SCHEMBL8304422 | 0.87 | CYP1B1 (0.63) | ABCB1ABCG2CYP1B1MEN1KMT2A | |
| SCHEMBL8427149 | 0.87 | KDM4E (0.57) | ABCB1ABCG2CYP1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |