Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775923 | 0.79 | KIF11 (0.44) | KIF11TSHRPDE2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL15775480 | 0.78 | KIF11 (0.42) | KIF11TSHRPDE2AALDH1A1KDM4E | |
| SCHEMBL22363709 | 0.77 | HDAC4 (0.37) | KIF11TSHRALDH1A1MAPTNPC1 | |
| SCHEMBL11043704 | 0.77 | KIF11 (0.45) | KIF11TSHRLMNATYRPDE2A | |
| SCHEMBL31259082 | 0.76 | FFAR1 (0.42) | KIF11TSHRLMNATYRALDH1A1 | |
| SCHEMBL11452811 | 0.76 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL15775533 | 0.76 | HTT (0.40) | LMNATYRALDH1A1MAPTHPGD | |
| SCHEMBL1199765 | 0.75 | TSHR (0.54) | KIF11TSHRLMNATYRALDH1A1 | |
| SCHEMBL18892170 | 0.75 | TSHR (0.48) | KIF11TSHRLMNATYRPDE2A | |
| SCHEMBL6683728 | 0.75 | TSHR (0.48) | KIF11TSHRLMNATYRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103030575-B | Double-cyano acidamide compound, and synthetic method and application of compound | CHINA AGRICULTURAL UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-103030575-A | Double-cyano acidamide compound, and synthetic method and application of compound | UNIV CHINA AGRICULTURAL | 2013-04-10 | — | — | CN | disclosed |
| CN-1919838-A | Alpha-cyano-N-benzylpyrazoamide compound, preparation method and pest control agent thereof as active component | JIANGSU PESTICIDE RES INST CO (CN) | 2007-02-28 | — | — | CN | disclosed |
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5378708-A | Agricultural pesticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |