Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957510 | 0.83 | MAPK1 (0.57) | RAB9AMAPK1HTTMEN1ALDH1A1 | |
| SCHEMBL6956263 | 0.82 | PPARG (0.45) | TNFPPARGFFAR1PPARAPPARD | |
| SCHEMBL6954580 | 0.81 | TNF (0.41) | TNFPPARGFFAR1PPARAPPARD | |
| SCHEMBL6949013 | 0.79 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6952622 | 0.79 | TNF (0.44) | TNFPPARGFFAR1PPARAPPARD | |
| SCHEMBL6952202 | 0.78 | PPARG (0.45) | TNFPPARGFFAR1PPARAPPARD | |
| SCHEMBL6952396 | 0.78 | MEN1 (0.46) | TNFPPARGPPARAPPARDRAB9A | |
| SCHEMBL6957273 | 0.78 | PPARG (0.47) | TNFPPARGPPARAPPARDRAB9A | |
| SCHEMBL8305576 | 0.76 | ACKR3 (0.49) | PPARGRAB9AGAACYP2C9HPGD | |
| SCHEMBL6957154 | 0.76 | TNF (0.49) | TNFPPARGFFAR1PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |