Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 4/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306226 | 0.80 | — | — | |
| SCHEMBL8302096 | 0.76 | BRS3 (0.32) | BRS3 | |
| SCHEMBL8521808 | 0.75 | BRS3 (0.32) | BRS3 | |
| SCHEMBL9652691 | 0.72 | HSD11B1 (0.45) | XDHGP6BRS3 | |
| SCHEMBL8303502 | 0.72 | — | — | |
| SCHEMBL8521755 | 0.69 | — | — | |
| SCHEMBL8299425 | 0.68 | — | — | |
| SCHEMBL8300519 | 0.68 | — | — | |
| SCHEMBL11345633 | 0.68 | RARB (0.48) | — | |
| SCHEMBL6284038 | 0.66 | XDH (0.45) | XDHAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |