Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739300 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL29441579 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL6527575 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL9134643 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL8803706 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL2123602 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL1405688 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL30466039 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL5198321 | 0.76 | NOS2 (0.50) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL5198326 | 0.76 | NOS2 (0.50) | ALDH1A1KDM4EGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456826-B1 | AMINE DERIVATIVES | NIPPON SODA CO (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5612358-A | Pyridine compouds which have useful insecticidal activity | NIPPON SODA CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| US-5304566-A | Pyridine compounds which have useful insecticidal utility | NIPPON SODA CO., LTD (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0456826-A1 | AMINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| WO-1991004965-A1 | AMINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1991-04-18 | — | — | WO | disclosed |