SCHEMBL8305883

SCHEMBL8305883

CNCCN(CCO)CCNC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.46
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
PRMT1 Q99873 1/20 0.46
PRMT8 Q9NR22 1/20 0.46
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028381 1.00 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL5024036 0.97 PRMT3 (0.43) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15120484 0.91 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
Trolamine SCHEMBL4857518 0.89 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15427694 0.89 PRMT3 (0.54) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL17486783 0.89 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12969841 0.89 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL3319764 0.87 CYP1A2 (0.47) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL23223465 0.87 EPHX1 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL903463 0.87 EPHX1 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790986-B1 ANILINE DERIVATIVES ZENECA LTD (GB) 1999-01-20 EP disclosed