SCHEMBL5028381

SCHEMBL5028381

CNCCN(CCO)CCO

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.46
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
PRMT1 Q99873 1/20 0.46
PRMT8 Q9NR22 1/20 0.46
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8305883 1.00 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL5024036 0.97 PRMT3 (0.43) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15120484 0.91 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
Trolamine SCHEMBL4857518 0.89 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15427694 0.89 PRMT3 (0.54) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL17486783 0.89 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12969841 0.89 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL3319764 0.87 CYP1A2 (0.47) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL23223465 0.87 EPHX1 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL903463 0.87 EPHX1 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0876161-B1 CONTRAST MEDIA NYCOMED SALUTAR INC (US) 2001-11-21 EP claimed
EP-4328309-A2 LIPID COMPOSITION FUJIFILM Corporation (JP) 2024-02-28 EP disclosed
EP-3981435-B1 LIPID COMPOSITION FUJIFILM CORP (JP) 2023-08-16 EP disclosed
WO-2023141426-A1 ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2023-07-27 WO disclosed
US-9891523-B2 Photosensitive dry film and process for producing printed wiring board using the same TAIYO INK MFG. CO., LTD. (JP) 2018-02-13 US disclosed
US-20170190729-A1 POLYENE MACROLIDE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2017-07-06 US disclosed
US-20150382473-A1 PHOTOSENSITIVE DRY FILM AND PROCESS FOR PRODUCING PRINTED WIRING BOARD USING THE SAME TAIYO INK MANUFACTURING CO., LTD. (JP) 2015-12-31 US disclosed
EP-2670764-B1 C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2015-09-02 EP disclosed
US-20130310373-A1 PYRIMIDINE COMPOUND ASTELLAS PHARMA INC. (JP) 2013-11-21 US disclosed
US-8575094-B2 Use of type-B lantibiotic-based compounds having antimicrobial activity NOVACTA BIOSYSTEMS LIMITED (GB) 2013-11-05 US disclosed
US-20100016319-A1 ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) 2010-01-21 US disclosed
US-20090203583-A1 Use of Type-B Lantibiotic-Based Compounds having Antimicrobial Activity NOVACTA BIOSYSTEMS LIMITED (GB) 2009-08-13 US disclosed
US-7442791-B2 Aminoalkylamide substituted cyclohexyl derivatives HOFFMANN-LA ROCHE INC. (US) 2008-10-28 US disclosed
US-20080200465-A1 Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals GENESOFT PHARMACEUTICALS, INC. (US) 2008-08-21 US disclosed
US-7348427-B2 Antipathogenic benzamide compounds GENESOFT PHARMACEUTICALS, INC. (US) 2008-03-25 US disclosed
EP-1667962-A1 AMINOALKYLAMIDE SUBSTITUTED CYCLOHEXYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2006-06-14 EP disclosed
WO-2005028427-A1 AMINOALKYLAMIDE SUBSTITUTED CYCLOHEXYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2005-03-31 WO disclosed
US-20050065210-A1 Aminoalkylamide substituted cyclohexyl derivatives F. HOFFMANN-LA ROCHE AG (CH) 2005-03-24 US disclosed
EP-0876161-B1 CONTRAST MEDIA NYCOMED SALUTAR INC (US) 2001-11-21 EP disclosed
US-5491263-A DECYCLIZATION OF AN OXAZOLIDINONE WITH A SECONDARY AMINE OR A SECONDARY ALKANOLAMINE THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200465-A1 Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals IRF3, BCL3, L3MBTL3 PRMT3 122/4885CARM1 388/4885PRMT6 1279/4885
US-20170190729-A1 POLYENE MACROLIDE DERIVATIVE ERG28, RPL23, RPL10 PRMT3 4308/4885CARM1 4486/4885PRMT6 4274/4885
US-20130310373-A1 PYRIMIDINE COMPOUND CNR2, CNR1, P2RY2 PRMT3 3548/4885CARM1 3631/4885PRMT6 3611/4885
US-20100016319-A1 ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF UROD, UTS2R, SLC14A1 PRMT3 378/4885CARM1 520/4885PRMT6 660/4885
US-20050065210-A1 Aminoalkylamide substituted cyclohexyl derivatives LSS, CYP51A1, CYP46A1 PRMT3 478/4885CARM1 1123/4885PRMT6 1117/4885
US-20090203583-A1 Use of Type-B Lantibiotic-Based Compounds having Antimicrobial Activity MTPN, NISCH, VIP PRMT3 4184/4885CARM1 4884/4885PRMT6 3445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.