Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL28568630 | 0.90 | CES2 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7759093 | 0.90 | CES2 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL29036106 | 0.90 | CES2 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL28888259 | 0.90 | CES2 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| Adipic Acid SCHEMBL28590164 | 0.90 | MEN1 (0.57) | PPARAHDAC11TSHRKMT2ATDP1 | |
| Dodecane SCHEMBL28370737 | 0.90 | PARP1 (0.57) | TSHRKMT2ATDP1MEN1HSD17B10 | |
| Adipic Acid SCHEMBL28590163 | 0.90 | MEN1 (0.57) | PPARAHDAC11TSHRKMT2ATDP1 | |
| Benzamide SCHEMBL8383228 | 0.88 | CES2 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Isophthalic Acid SCHEMBL735784 | 0.85 | AKR1B1 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Benzamide SCHEMBL29027531 | 0.83 | TSHR (0.59) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9304428-B2 | Full-color image-forming method | CANON KABUSHIKI KAISHA (JP) | 2016-04-05 | — | — | US | disclosed |
| EP-2642342-B1 | Black Toner and full-color image-forming method | CANON KK (JP) | 2015-12-09 | — | — | EP | disclosed |
| EP-2642343-B1 | Magenta toner and full-color image-forming method | CANON KK (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140219684-A1 | FULL-COLOR IMAGE-FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2014-08-07 | — | — | US | disclosed |
| US-8728689-B2 | Full-color image-forming method | CANON KABUSHIKI KAISHA (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-1715387-B1 | Toner, method of preparing the toner and apparatus for preparing the toner | RICOH CO LTD (JP) | 2014-02-26 | — | — | EP | disclosed |
| EP-2642342-A1 | Black Toner and full-color image-forming method | Canon Kabushiki Kaisha (JP) | 2013-09-25 | — | — | EP | disclosed |
| EP-2642343-A1 | Magenta toner and full-color image-forming method | Canon Kabushiki Kaisha (JP) | 2013-09-25 | — | — | EP | disclosed |
| EP-2110710-B1 | CYAN TONER AND FULL COLOR IMAGE FORMING METHOD | CANON KK (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-1960840-B1 | DEVELOPER FOR REPLENISHMENT AND IMAGE FORMING METHOD | CANON KK (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8142972-B2 | Developer for replenishment and image forming method | CANON KABUSHIKI KAISHA (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20110151373-A1 | FULL-COLOR IMAGE-FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2110710-A1 | CYAN TONER, MAGENTA TONER, YELLOW TONER, BLACK TONER, AND FULL COLOR IMAGE FORMING METHOD | Canon Kabushiki Kaisha (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-7553599-B2 | Toner, method of preparing the toner and apparatus for preparing the toner | RICOH COMPANY, LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20090123856-A1 | DEVELOPER FOR REPLENISHMENT AND IMAGE FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2009-05-14 | — | — | US | disclosed |
| US-20080247788-A1 | CYAN TONER, MAGENTA TONER, YELLOW TONER, BLACK TONER, AND FULL-COLOR IMAGE-FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2008-10-09 | — | — | US | disclosed |
| EP-1960840-A1 | DEVELOPER FOR REPLENISHMENT AND IMAGE FORMING METHOD | Canon Kabushiki Kaisha (JP) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007066800-A1 | DEVELOPER FOR REPLENISHMENT AND IMAGE FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | WO | disclosed |
| US-20060240354-A1 | Toner, method of preparing the toner and apparatus for preparing the toner | RICOH COMPANY, LTD. (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1715387-A2 | Toner, method of preparing the toner and apparatus for preparing the toner | Ricoh Company, Ltd. (JP) | 2006-10-25 | — | — | EP | disclosed |