Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305923 | 1.00 | ALOX5 (0.50) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL8307175 | 0.81 | ALOX5 (0.65) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL8310117 | 0.80 | ALOX5 (0.63) | ALOX5HRH1EPHX2 | |
| SCHEMBL8308636 | 0.80 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8308637 | 0.80 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL9046213 | 0.79 | ALOX5 (0.65) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL8884953 | 0.69 | ALOX5 (0.46) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL9047843 | 0.69 | ALOX5 (0.70) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL9047887 | 0.69 | ALOX5 (0.80) | ALOX5HRH1EPHX2ACACBACACA | |
| SCHEMBL9047489 | 0.68 | ALOX5 (0.61) | ALOX5HRH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667855-B1 | SUBSTITUTED ARYLALKYNYL- AND HETEROARYLALKYNYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LAB (US) | 1999-03-24 | — | — | EP | disclosed |