Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.65 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109641 | 0.85 | ALOX5 (0.80) | ALOX5EPHX2ACACBACACAHRH1 | |
| SCHEMBL2109638 | 0.85 | ALOX5 (0.80) | ALOX5EPHX2ACACBACACAHRH1 | |
| SCHEMBL8307765 | 0.84 | ALOX5 (0.67) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8307767 | 0.84 | ALOX5 (0.67) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8309174 | 0.83 | ALOX5 (0.76) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8309173 | 0.83 | ALOX5 (0.76) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8305923 | 0.81 | ALOX5 (0.50) | ALOX5EPHX2ACACBACACAHRH1 | |
| SCHEMBL8305926 | 0.81 | ALOX5 (0.50) | ALOX5EPHX2ACACBACACAHRH1 | |
| SCHEMBL8303836 | 0.81 | ALOX5 (0.79) | ALOX5EPHX2ACACBACACAHRH1 | |
| SCHEMBL8303838 | 0.81 | ALOX5 (0.79) | ALOX5EPHX2ACACBACACAHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667855-B1 | SUBSTITUTED ARYLALKYNYL- AND HETEROARYLALKYNYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LAB (US) | 1999-03-24 | — | — | EP | disclosed |