Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305966 | 1.00 | L3MBTL1 (0.49) | L3MBTL1NR1I2NR1H3MEN1KMT2A | |
| SCHEMBL8305035 | 0.82 | PPARA (0.51) | L3MBTL1MEN1KMT2AGAAKDM4E | |
| SCHEMBL8305033 | 0.82 | PPARA (0.51) | L3MBTL1MEN1KMT2AGAAKDM4E | |
| SCHEMBL8390039 | 0.79 | NR1I2 (0.48) | L3MBTL1NR1I2NR1H3MEN1KMT2A | |
| SCHEMBL8310032 | 0.79 | NR1I2 (0.56) | NR1I2NR1H3MEN1KMT2ALIMK2 | |
| SCHEMBL4476867 | 0.77 | LMNA (0.69) | L3MBTL1MEN1KMT2AMAPK1LMNA | |
| SCHEMBL4476864 | 0.77 | LMNA (0.69) | L3MBTL1MEN1KMT2AMAPK1LMNA | |
| SCHEMBL5610797 | 0.74 | LMNA (0.56) | L3MBTL1MAPK1LMNAMAPTNPC1 | |
| SCHEMBL5610798 | 0.74 | LMNA (0.56) | L3MBTL1MAPK1LMNAMAPTNPC1 | |
| SCHEMBL12673467 | 0.74 | SIRT2 (0.61) | NR1I2NR1H3MEN1KMT2ALIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |