Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306623 | 0.89 | KDM4C (0.40) | KDM4CNPC1RAB9AL3MBTL1MET | |
| SCHEMBL8309323 | 0.85 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1ADORA3 | |
| SCHEMBL8304994 | 0.84 | L3MBTL1 (0.45) | KDM4CNPC1RAB9AL3MBTL1ADORA3 | |
| SCHEMBL6933894 | 0.84 | KDM4C (0.44) | KDM4CNPC1RAB9AL3MBTL1CYP1A2 | |
| SCHEMBL5610112 | 0.83 | NPC1 (0.48) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL8308439 | 0.82 | KDM4C (0.37) | KDM4CNPC1RAB9AL3MBTL1ADORA3 | |
| SCHEMBL8305428 | 0.78 | KDM4C (0.37) | KDM4CNPC1RAB9AL3MBTL1CYP11B1 | |
| SCHEMBL8307195 | 0.77 | RAB9A (0.45) | KDM4CNPC1RAB9AL3MBTL1ADORA3 | |
| SCHEMBL8304159 | 0.77 | KDM4C (0.41) | KDM4CNPC1RAB9AL3MBTL1ADORA3 | |
| SCHEMBL8309584 | 0.75 | KDM4C (0.40) | KDM4CNPC1RAB9AL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |