Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523671 | 0.88 | KDM1A (0.46) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL4401738 | 0.85 | CA12 (0.53) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL3522928 | 0.85 | PAOX (0.59) | PAOXKDM1AHPGDDUSP3KEAP1 | |
| SCHEMBL8310197 | 0.82 | ACE2 (0.50) | KDM1AACE2SMN1; SMN2CA12CA1 | |
| SCHEMBL721355 | 0.81 | PAOX (0.64) | PAOXKDM1AHPGDDUSP3KEAP1 | |
| SCHEMBL8310938 | 0.81 | KEAP1 (0.64) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL8310934 | 0.81 | KDM1A (0.48) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL29235706 | 0.81 | KDM1A (0.48) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL13912969 | 0.81 | PAOX (0.51) | PAOXKDM1AACE2HPGDDUSP3 | |
| SCHEMBL8306310 | 0.81 | ALDH1A1 (0.53) | PAOXKDM1AACE2HPGDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5821246-A | USEFUL AS TYROSINE KINASE INHIBITORS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | ZENECA LIMITED (GB) | 1998-10-13 | — | — | US | disclosed |
| EP-0790986-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015118-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |