Coumarinic Acid Methyl Ether

Coumarinic Acid Methyl Ether

SCHEMBL83064

COc1ccccc1/C=C/C(=O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.77
TFEB P19484 1/20 0.77
KDM4E B2RXH2 3/20 0.74
MAPT P10636 4/20 0.73
NPC1 O15118 3/20 0.73
RAB9A P51151 2/20 0.73
LMNA P02545 2/20 0.73
BCHE P06276 1/20 0.73
GAA P10253 1/20 0.71
HTT P42858 1/20 0.67
MAPK1 P28482 2/20 0.66
ATM Q13315 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
LY96 Q9Y6Y9 1/20 0.64
MAOB P27338 3/20 0.62
AR P10275 1/20 0.62
HPGD P15428 3/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2D6 P10635 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarinic Acid Methyl Ether SCHEMBL29369917 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL79060 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL714857 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL4743620 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL10437229 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL8351832 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL28250887 0.95 NFE2L2 (0.71) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL22092089 0.93 KDM4E (0.68) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL2468602 0.93 NFE2L2 (0.68) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL28320175 0.93 NFE2L2 (0.68) NFE2L2TFEBKDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8759 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4279532-B1 CROSSLINKED POLYGLYCEROL PARTIAL ESTERS EVONIK OPERATIONS GMBH (DE) 2026-03-25 EP claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
EP-3886791-B1 CLAY MASK COMPOSITION AND METHOD FOR USING THE SAME UNILEVER GLOBAL IP LTD (GB) 2025-11-12 EP claimed
EP-3730122-B1 TRANSDERMAL DELIVERY COMPLEX USING METAL-ORGANIC FRAMEWORK AND NANOCELLULOSE H&A PHARMACHEM CO LTD (KR) 2025-02-26 EP claimed
CN-119431432-A Andrographolide diester derivative, preparation method and application 西北农林科技大学 2025-02-14 CN claimed
CN-119385892-A Yellow Bai Fangshai liposome dispersion liquid, preparation method thereof and sun protection emulsion 广东医科大学 2025-02-07 CN claimed
CN-119215104-A Traditional Chinese medicine extract and application thereof in preparation of cell necrotic apoptosis inhibitor 河南中医药大学 2024-12-31 CN claimed
US-12168065-B2 Cosmetic composition for UV-protection that increases UV protection efficiency by means of UV light LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-12-17 US claimed
CN-118541136-A Skin microbiome friendly sunscreens 巴斯夫欧洲公司 2024-08-23 CN claimed
EP-0456459-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
WO-1993013742-A1 PREPARATION FOR SKIN USE COSMETICS DEVELOPMENT COMPANY LIMITED (GB) 1993-07-22 WO claimed
US-5017365-A Impregnated fibrous sheet SOLARCARE TECHNOLOGIES CORPORATION (US) 1991-05-21 US claimed
EP-0356355-A1 Ophthalmic liquid for sun glasses Baron, Neville A. (US) 1990-02-28 EP claimed
EP-0321929-A1 Sunscreen composition containing copper 3,5-diisopropyl salicylate ESTEE LAUDER INC. (US) 1989-06-28 EP claimed
EP-0275719-A2 Ultraviolet absorbing compounds and formulations including same Richardson-Vicks, Inc. (US) 1988-07-27 EP claimed
EP-0185066-A1 UNIV PASTEUR 1986-06-25 EP claimed
WO-1986000304-A1 SULPHUR-CONTAINING DERIVATIVES OF PARA-METHOXYCINNAMIC ACID, PRODUCTION PROCESSES THEREOF, DERMO-PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM AND APPLICATIONS UNIVERSITE LOUIS PASTEUR (STRASBOURG I) (FR) 1986-01-16 WO claimed
US-4535130-A SUNSCREEN AGENTS, SKIN CREAMS SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) 1985-08-13 US claimed
US-4435545-A AN EPOXY-CONTAINING POLYOLEFIN OR ACRYLATE IS REACTED WITH SALICYLIC ACID, CINNAMIC ACID OR METHOXYCINNAMIC ACID SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) 1984-03-06 US claimed