Coumarinic Acid Methyl Ether

Coumarinic Acid Methyl Ether

SCHEMBL79060

COc1ccccc1C=CC(=O)O

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.77
TFEB P19484 1/20 0.77
KDM4E B2RXH2 3/20 0.74
MAPT P10636 4/20 0.73
NPC1 O15118 3/20 0.73
RAB9A P51151 2/20 0.73
LMNA P02545 2/20 0.73
BCHE P06276 1/20 0.73
GAA P10253 1/20 0.71
HTT P42858 1/20 0.67
MAPK1 P28482 2/20 0.66
ATM Q13315 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
LY96 Q9Y6Y9 1/20 0.64
MAOB P27338 3/20 0.62
AR P10275 1/20 0.62
HPGD P15428 3/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2D6 P10635 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarinic Acid Methyl Ether SCHEMBL29369917 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL83064 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL714857 1.00 NFE2L2 (0.77) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL4743620 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL10437229 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL8351832 0.98 NFE2L2 (0.74) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL28250887 0.95 NFE2L2 (0.71) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL22092089 0.93 KDM4E (0.68) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL2468602 0.93 NFE2L2 (0.68) NFE2L2TFEBKDM4EMAPTNPC1
Coumarinic Acid Methyl Ether SCHEMBL28320175 0.93 NFE2L2 (0.68) NFE2L2TFEBKDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-119431432-A Andrographolide diester derivative, preparation method and application 西北农林科技大学 2025-02-14 CN claimed
CN-119215104-A Traditional Chinese medicine extract and application thereof in preparation of cell necrotic apoptosis inhibitor 河南中医药大学 2024-12-31 CN claimed
CN-118266572-A Application of 3-methoxyphenyl-2-acrylic compound as bitter taste inhibitor 华南理工大学 2024-07-02 CN claimed
CN-118027276-A Multipolymer, preparation method and application thereof, negative electrode slurry, negative electrode plate and lithium ion battery 北京卫蓝新能源科技有限公司 2024-05-14 CN claimed
US-20230390195-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS DELPOR, INC. 2023-12-07 US claimed
CN-114163313-B Method for selectively synthesizing EZ-stilbene by coupling ruthenium-catalyzed aryl diazonium salt with cinnamic acid 中山大学 2023-11-03 CN claimed
CN-116687962-A Composition for preventing or treating diabetes and application thereof 青岛大学 2023-09-05 CN claimed
US-20220280494-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2022-09-08 US claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050161666-A1 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-07-28 US claimed
US-6916890-B1 Thermally reworkable epoxy resins and compositions based thereon HENKEL CORPORATION (US) 2005-07-12 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1526584-A2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same Samsung Electronics Co., Ltd (KR) 2005-04-27 EP claimed
WO-2003031492-A1 THERMALLY REWORKABLE EPOXY RESINS AND COMPOSITIONS BASED THEREO N HENKEL CORPORATION (US) 2003-04-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 NFE2L2 1266/4885TFEB 957/4885KDM4E 1814/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 NFE2L2 3435/4885TFEB 1404/4885KDM4E 1567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.