Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LDLR | P01130 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453399 | 0.79 | HPGDS (0.58) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL822807 | 0.78 | HPGDS (0.77) | HPGDSALDH1A1CYP11B1CYP11B2COMT | |
| SCHEMBL5376019 | 0.76 | HPGDS (0.54) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL27216943 | 0.76 | HPGDS (0.54) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL28069527 | 0.76 | HPGDS (0.54) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL27322957 | 0.76 | HPGDS (0.54) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL7913638 | 0.76 | KDM4E (0.58) | HPGDSALDH1A1HSD11B1KDM4EMAPT | |
| SCHEMBL6977000 | 0.76 | CYP11B1 (0.56) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL7912421 | 0.74 | AVPR1A (0.44) | HPGDSALDH1A1KDM4EMAPTCHEK1 | |
| SCHEMBL13843725 | 0.74 | HPGDS (0.53) | HPGDSALDH1A1HSD11B1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923573-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006716-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |