SCHEMBL7913638

SCHEMBL7913638

CCn1c(Cl)cnc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
HSD17B10 Q99714 1/20 0.58
BRD4 O60885 1/20 0.47
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
NLRP3 Q96P20 1/20 0.43
TSHR P16473 1/20 0.42
HPGDS O60760 2/20 0.42
NR1H3 Q13133 1/20 0.42
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
CHEK1 O14757 1/20 0.40
MAPT P10636 1/20 0.40
LIMK1 P53667 1/20 0.40
MAPK14 Q16539 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16193332 0.80 KDM4E (0.59) KDM4EHSD17B10ADORA3ADORA2AADORA2B
SCHEMBL8306426 0.76 HPGDS (0.54) KDM4EHSD17B10BRD4HPGDSNR1H3
SCHEMBL13843809 0.75 KDM4E (0.54) KDM4EHSD17B10ADORA3ADORA2AADORA2B
SCHEMBL4030659 0.75 KDM4E (0.54) KDM4EHSD17B10BRD4ADORA3ADORA2A
SCHEMBL1184137 0.72
SCHEMBL11768659 0.71 KDM4E (0.50) KDM4EHSD17B10ADORA2AADORA2BALDH1A1
SCHEMBL7912421 0.70 AVPR1A (0.44) KDM4EHSD17B10TSHRHPGDSALDH1A1
SCHEMBL761987 0.70 KDM4E (0.49) KDM4EHSD17B10ADORA3ADORA2AADORA2B
SCHEMBL18419644 0.69 KDM4E (0.47) KDM4EHSD17B10TSHRHPGDSALDH1A1
SCHEMBL19419968 0.69 KDM4E (0.47) KDM4EHSD17B10ADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed