Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 5/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8310148 | 0.99 | BRS3 (0.48) | BRS3CYP17A1CYP11B1CYP11B2LTA4H | |
| SCHEMBL8106523 | 0.84 | BRS3 (0.54) | BRS3CYP11B1CYP11B2HRH3KDM1A | |
| SCHEMBL7919393 | 0.84 | BRS3 (0.62) | BRS3CYP11B1CYP11B2HRH3 | |
| Hydrochloric Acid SCHEMBL8521500 | 0.83 | BRS3 (0.61) | BRS3CYP11B1CYP11B2HRH3 | |
| SCHEMBL8105207 | 0.83 | BRS3 (0.53) | BRS3CYP11B1CYP11B2HRH3SCN10A | |
| SCHEMBL8106516 | 0.80 | KIF11 (0.54) | BRS3HRH3KDM1A | |
| Hydrochloric Acid SCHEMBL8311538 | 0.79 | KIF11 (0.52) | BRS3HRH3KDM1A | |
| SCHEMBL8498703 | 0.78 | BRS3 (0.49) | BRS3CYP11B1CYP11B2HRH3ALDH1A1 | |
| SCHEMBL8107069 | 0.78 | BRS3 (0.51) | BRS3CYP11B1CYP11B2HRH3KDM1A | |
| SCHEMBL8097365 | 0.77 | BRS3 (0.50) | BRS3HRH3TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036886-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |