Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304836 | 0.92 | CYP1B1 (0.66) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 | |
| SCHEMBL8429084 | 0.88 | CYP1B1 (0.59) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 | |
| SCHEMBL8304767 | 0.88 | CYP1B1 (0.76) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL7306849 | 0.87 | MAPT (0.74) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL4575435 | 0.85 | CYP1B1 (0.71) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 | |
| SCHEMBL7318625 | 0.84 | CYP1B1 (0.56) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 | |
| SCHEMBL1976256 | 0.84 | MAPT (0.67) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL8304325 | 0.84 | CYP1B1 (0.54) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 | |
| SCHEMBL8066758 | 0.84 | L3MBTL1 (0.72) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL8429585 | 0.83 | CYP1B1 (0.56) | MAPTCYP1B1CYP1A1CYP1A2ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |