Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.71 |
| ▸ | KDM1A | O60341 | 2/20 | 0.71 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.71 |
| ▸ | XDH | P47989 | 1/20 | 0.71 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976256 | 0.89 | MAPT (0.67) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL8306488 | 0.87 | MAPT (0.64) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL5792042 | 0.86 | MAPT (0.91) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL974548 | 0.85 | MAPT (1.00) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL26117114 | 0.85 | CYP1B1 (0.86) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL30376285 | 0.85 | MAPT (1.00) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL7315053 | 0.85 | MAPT (0.62) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL8064295 | 0.85 | L3MBTL1 (0.71) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL8066758 | 0.84 | L3MBTL1 (0.72) | MAPTABCB1CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL14048682 | 0.83 | MAPT (0.78) | MAPTABCB1CYP1B1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |