Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858241 | 0.77 | NAAA (0.48) | NAAAFAAHALDH1A1KMT2ATSHR | |
| SCHEMBL3019770 | 0.75 | PKM (0.49) | NAAAFAAHALDH1A1LMNAPOLB | |
| SCHEMBL11985467 | 0.73 | NAAA (0.50) | NAAAFAAHALDH1A1POLBKMT2A | |
| SCHEMBL20715297 | 0.72 | NAAA (0.47) | NAAAFAAHALDH1A1KMT2ATSHR | |
| SCHEMBL14112017 | 0.71 | KMT2A (0.65) | ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL12561178 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL5213442 | 0.70 | CSNK1D (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL26333756 | 0.69 | CSNK1D (0.50) | ALDH1A1LMNATSHRNAMPTGRM5 | |
| SCHEMBL531434 | 0.69 | GRM2 (0.52) | NAAAFAAHPOLBKMT2A | |
| SCHEMBL4877349 | 0.69 | CSNK1D (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717738-B1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |