Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968887 | 1.00 | GFER (0.47) | GFERNPSR1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7735969 | 0.88 | NPSR1 (0.58) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL7731091 | 0.88 | NPSR1 (0.45) | NPSR1SMN1; SMN2L3MBTL1HSD11B1SOAT1 | |
| SCHEMBL4177495 | 0.84 | HSD11B1 (0.45) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL4177490 | 0.84 | HSD11B1 (0.45) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL4177483 | 0.84 | HSD11B1 (0.45) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL4192177 | 0.81 | NPSR1 (0.39) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL4192176 | 0.81 | NPSR1 (0.39) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 | |
| SCHEMBL4183121 | 0.81 | SMN1; SMN2 (0.37) | GFERNPSR1SMN1; SMN2L3MBTL1HSD11B1 | |
| SCHEMBL4192183 | 0.81 | NPSR1 (0.39) | GFERNPSR1SMN1; SMN2HSD11B1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896577-A1 | TAXANE DERIVATIVES HAVING A PYRIDIL SUBSTITUTED C13 SIDE CHAIN, THEIR PREPARATION AND THEIR USE AS ANTI-TUMOR AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997028156-A1 | TAXANE DERIVATIVES HAVING A PYRIDYL SUBSTITUTED C13 SIDE CHAIN, THEIR PREPARATION AND THEIR USE AS ANTI-TUMOR AGENTS | SCHERING AKTIENGESELLSCHAFT PATENTE (DE) | 1997-08-07 | — | — | WO | disclosed |