Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735969 | 0.88 | NPSR1 (0.58) | NPSR1SMN1; SMN2MEN1KMT2AHSD11B1 | |
| SCHEMBL6968887 | 0.88 | GFER (0.47) | NPSR1SMN1; SMN2L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL8306745 | 0.88 | GFER (0.47) | NPSR1SMN1; SMN2L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL8952493 | 0.81 | CACNA1G (0.39) | NPSR1MEN1KMT2AP2RX3ALDH1A1 | |
| SCHEMBL4177490 | 0.77 | HSD11B1 (0.45) | NPSR1SMN1; SMN2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL4177483 | 0.77 | HSD11B1 (0.45) | NPSR1SMN1; SMN2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL4177495 | 0.77 | HSD11B1 (0.45) | NPSR1SMN1; SMN2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL4184940 | 0.77 | NPSR1 (0.39) | NPSR1SMN1; SMN2MEN1KMT2AHSD11B1 | |
| SCHEMBL4179392 | 0.75 | HSD11B1 (0.39) | NPSR1SMN1; SMN2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL4179397 | 0.75 | HSD11B1 (0.39) | NPSR1SMN1; SMN2KMT2AHSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-B1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | UNIV NEW YORK STATE RES FOUND (US) | 2002-12-04 | — | — | EP | disclosed |
| US-5705508-A | FORMING TAXOL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-01-06 | — | — | US | disclosed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| US-5475011-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-12-12 | — | — | US | disclosed |