SCHEMBL8306756

SCHEMBL8306756

Cc1nc(-n2nn[nH]c2=O)cs1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.39
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
MMP12 P39900 1/20 0.31
RAB9A P51151 1/20 0.31
PKM P14618 1/20 0.31
LRRK2 Q5S007 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8304709 0.73 L3MBTL1 (0.43) NPC1MAPTRAB9AIRAK4
SCHEMBL8304144 0.69
SCHEMBL8307375 0.68 COMT (0.34)
SCHEMBL8304805 0.68
SCHEMBL8307444 0.68
SCHEMBL8307466 0.68
SCHEMBL8308484 0.68
SCHEMBL8306630 0.67 LMNA (0.39) MAPT
SCHEMBL8302524 0.67
SCHEMBL8303401 0.67 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed