Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558904 | 0.82 | SMN1; SMN2 (0.53) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19700944 | 0.78 | ALDH1A1 (0.41) | HPGDSMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL12777764 | 0.77 | TSHR (0.49) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8308697 | 0.76 | MAPT (0.37) | SMN1; SMN2ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL1354839 | 0.76 | SMN1; SMN2 (0.47) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29559950 | 0.76 | SMN1; SMN2 (0.47) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27928235 | 0.76 | POLB (0.39) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8307192 | 0.75 | SMN1; SMN2 (0.46) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12777765 | 0.75 | PKM (0.43) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL23095997 | 0.74 | SMN1; SMN2 (0.53) | POLBHPGDSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |