Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158872 | 0.82 | OPRM1 (0.61) | PDE4BOPRM1NPC1RAB9AMAP4K4 | |
| SCHEMBL27300666 | 0.79 | PDE4B (0.50) | PDE4BOPRM1HAO1MEN1KMT2A | |
| SCHEMBL27299799 | 0.79 | PDE4B (0.52) | PDE4BOPRM1MEN1KMT2AMAP4K4 | |
| SCHEMBL921076 | 0.79 | CYP19A1 (0.50) | PDE4BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL27297116 | 0.78 | PDE4B (0.48) | PDE4BOPRM1MEN1KMT2AMAP4K4 | |
| SCHEMBL31473410 | 0.78 | PDE4B (0.48) | PDE4BOPRM1MEN1KMT2AMAP4K4 | |
| SCHEMBL27299558 | 0.78 | PDE4B (0.48) | PDE4BOPRM1MEN1KMT2AMAP4K4 | |
| SCHEMBL24665295 | 0.76 | OPRM1 (0.52) | PDE4BOPRM1HAO1MAP4K4FPR2 | |
| SCHEMBL6160870 | 0.76 | MEN1 (0.58) | PDE4BOPRM1MEN1KMT2AMAP4K4 | |
| SCHEMBL8237112 | 0.76 | KDM4E (0.54) | PDE4BOPRM1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891975-A1 | PYRAZOLES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |