Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222107 | 0.84 | OPRM1 (0.50) | OPRM1PDE4BCYP19A1GABRA5MAP4K4 | |
| SCHEMBL8237112 | 0.83 | KDM4E (0.54) | OPRM1PDE4BMAP4K4ALDH1A1HTT | |
| SCHEMBL24665295 | 0.83 | OPRM1 (0.52) | OPRM1PDE4BCYP19A1MAP4K4MAOB | |
| SCHEMBL6160870 | 0.83 | MEN1 (0.58) | OPRM1PDE4BCYP19A1MAP4K4ALOX5AP | |
| SCHEMBL8306759 | 0.82 | PDE4B (0.52) | OPRM1PDE4BGABRA5MAP4K4ALOX5AP | |
| SCHEMBL11998352 | 0.82 | ACACB (0.46) | OPRM1ACACBLTA4HMAP4K4ALDH1A1 | |
| SCHEMBL1222601 | 0.81 | OPRM1 (0.51) | OPRM1PDE4BACACBMAP4K4ALDH1A1 | |
| SCHEMBL31473410 | 0.81 | PDE4B (0.48) | OPRM1PDE4BCYP19A1MAP4K4ALOX5AP | |
| SCHEMBL27297116 | 0.81 | PDE4B (0.48) | OPRM1PDE4BCYP19A1MAP4K4ALOX5AP | |
| SCHEMBL27299558 | 0.81 | PDE4B (0.48) | OPRM1PDE4BACACBMAP4K4ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011250-B | Synthetic method and application of 2- (2, 6-dichlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |
| US-20050165064-A1 | Novel thiol derivative, process for producing the same and use thereof | TAKEDA PHARMACEUTICALS NORTH AMERICA, INC. | 2005-07-28 | — | — | US | disclosed |
| EP-1500658-A1 | NOVEL THIOL DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165064-A1 | Novel thiol derivative, process for producing the same and use thereof | TST, QSOX1, MMP1 | OPRM1 2125/4885PDE4B 4827/4885CYP19A1 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.