Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.64 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.64 |
| ▸ | XDH | P47989 | 3/20 | 0.64 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305421 | 0.89 | MAOB (0.58) | IP6K2MAOAMAOBFLT3MKNK2 | |
| SCHEMBL8308746 | 0.86 | PLG (0.52) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8306319 | 0.86 | PLG (0.52) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8309077 | 0.86 | PLG (0.52) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8427199 | 0.84 | EGFR (0.56) | CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8309435 | 0.83 | PLG (0.48) | IP6K2MAOAMAOBFLT3CYP19A1 | |
| SCHEMBL8306911 | 0.82 | PLG (0.47) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8431060 | 0.82 | PLG (0.47) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8309769 | 0.82 | PLG (0.47) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL8308176 | 0.82 | AKT1 (0.52) | MEN1MAPTKMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |