Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309077 | 0.89 | PLG (0.52) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8308746 | 0.89 | PLG (0.52) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8306319 | 0.89 | PLG (0.52) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8305421 | 0.85 | MAOB (0.58) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8427199 | 0.83 | EGFR (0.56) | EGFRRETKDRQPCT | |
| SCHEMBL8306760 | 0.83 | CYP1B1 (0.64) | PLGMAOBMAOAQPCTFLT3 | |
| SCHEMBL8309778 | 0.82 | POLH (0.50) | MAOBMAOAIP6K2 | |
| SCHEMBL8429280 | 0.80 | XDH (0.51) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8431060 | 0.78 | PLG (0.47) | PLGMAOBMAOAEGFRRET | |
| SCHEMBL8309769 | 0.78 | PLG (0.47) | PLGMAOBMAOAEGFRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | claimed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | claimed |