Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431060 | 1.00 | PLG (0.47) | PLGEGFRRETKDRQPCT | |
| SCHEMBL8309769 | 1.00 | PLG (0.47) | PLGEGFRRETKDRQPCT | |
| SCHEMBL8304672 | 0.94 | POLH (0.47) | PLGMAOBIP6K2MAOAKDM1A | |
| SCHEMBL8427267 | 0.87 | KDM4E (0.46) | EGFRRETKDRCYP1A2 | |
| SCHEMBL8309732 | 0.85 | — | — | |
| SCHEMBL8304422 | 0.84 | CYP1B1 (0.63) | PLGKDRMAOBIP6K2FLT3 | |
| SCHEMBL8305421 | 0.83 | MAOB (0.58) | PLGEGFRRETKDRQPCT | |
| SCHEMBL8306264 | 0.83 | CYP1B1 (0.63) | PLGMAOBIP6K2FLT3MKNK2 | |
| SCHEMBL8306760 | 0.82 | CYP1B1 (0.64) | PLGQPCTMAOBIP6K2FLT3 | |
| SCHEMBL8305061 | 0.82 | CYP1B1 (0.59) | PLGEGFRRETKDRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |