SCHEMBL8306987

SCHEMBL8306987

CC1(OCc2ccccc2)COC(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.41
ALDH1A1 P00352 2/20 0.41
IDO1 P14902 1/20 0.38
MAOA P21397 3/20 0.38
CCNB2 O95067 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36
CCND1 P24385 1/20 0.36
CCNB3 Q8WWL7 1/20 0.36
ELANE P08246 1/20 0.36
CTSG P08311 1/20 0.36
PRTN3 P24158 1/20 0.36
CTSV O60911 1/20 0.35
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
CTSC P53634 1/20 0.35
CTSF Q9UBX1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5070648 0.81 ALDH1A1 (0.42) MAOBALDH1A1MAOA
SCHEMBL7294202 0.78 TSHR (0.43) MAOBALDH1A1IDO1
SCHEMBL29552477 0.78 TSHR (0.43) MAOBALDH1A1IDO1
SCHEMBL1324048 0.76 POLB (0.42) MAOBALDH1A1MAOANPC1HPGD
SCHEMBL9008850 0.75 ALDH1A1 (0.37) MAOBALDH1A1MAOAELANE
SCHEMBL2028476 0.74 ALDH1A1 (0.45) ALDH1A1NPC1RAB9A
SCHEMBL5838119 0.73 MAOB (0.42) MAOBALDH1A1IDO1MAOAELANE
SCHEMBL28772875 0.72 ALDH1A1 (0.43) MAOBALDH1A1MAOA
SCHEMBL846827 0.70 ALDH1A1 (0.47) ALDH1A1NPC1RAB9A
SCHEMBL28960387 0.69 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835254-B1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1999-09-01 EP claimed
EP-0835254-A1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1998-04-15 EP claimed
WO-1996038444-A1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1996-12-05 WO claimed