Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304293 | 0.81 | DRD2 (0.70) | HTR1ADRD2 | |
| SCHEMBL8307032 | 0.79 | HRH3 (0.50) | HTR1ADRD2 | |
| SCHEMBL8303446 | 0.79 | HTR1A (0.93) | HTR1ADRD2 | |
| SCHEMBL8303876 | 0.78 | HTR1A (0.61) | HTR1ADRD2 | |
| SCHEMBL2303131 | 0.77 | HTR1A (0.73) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL4177860 | 0.77 | HTR1A (0.71) | HTR1ADRD2 | |
| SCHEMBL6173953 | 0.76 | HTR1A (0.65) | HTR1A | |
| SCHEMBL8691042 | 0.76 | HTR1A (0.65) | HTR1A | |
| SCHEMBL31051744 | 0.76 | HTR1A (0.65) | HTR1A | |
| SCHEMBL8688384 | 0.76 | HTR1A (0.65) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574313-B1 | 1,4-Disubstituted piperazines for the treatment of disorders of the central nervous system and neuro-endocrine disorders | ADIR (FR) | 1999-10-06 | — | — | EP | claimed |
| US-5464834-A | Antidepressants, central nervous system | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | claimed |
| EP-0574313-A1 | 1,4-Disubstituted piperazines for the treatment of disorders of the central nervous system and neuro-endocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-12-15 | — | — | EP | claimed |
| EP-0574313-B1 | 1,4-Disubstituted piperazines for the treatment of disorders of the central nervous system and neuro-endocrine disorders | ADIR (FR) | 1999-10-06 | — | — | EP | disclosed |
| US-5464834-A | Antidepressants, central nervous system | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | disclosed |
| EP-0574313-A1 | 1,4-Disubstituted piperazines for the treatment of disorders of the central nervous system and neuro-endocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-12-15 | — | — | EP | disclosed |