Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 8/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PROC | P04070 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6324175 | 0.99 | PDE5A (0.39) | PDE5AHPGDCDK1F10PRSS1 | |
| SCHEMBL2998619 | 0.89 | F10 (0.46) | PDE5AHPGDCDK1F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6326771 | 0.88 | F10 (0.45) | PDE5AHPGDCDK1F10PRSS1 | |
| SCHEMBL6323093 | 0.88 | F10 (0.40) | PDE5AHPGDCDK1F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6324262 | 0.87 | PDE5A (0.40) | PDE5AHPGDCDK1F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6321548 | 0.85 | PDE5A (0.37) | PDE5AHPGDF10PRSS1ALDH1A1 | |
| SCHEMBL8306090 | 0.84 | VNN1 (0.40) | PDE5AHPGDCDK1F10PRSS1 | |
| SCHEMBL8311305 | 0.77 | PDE5A (0.39) | PDE5AHPGDCDK1ALDH1A1LMNA | |
| SCHEMBL2991625 | 0.77 | F10 (0.41) | PDE5AHPGDCDK1F10PRSS1 | |
| SCHEMBL2995398 | 0.76 | CDK1 (0.42) | PDE5AHPGDCDK1F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |