Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14936823 | 0.85 | KDM4E (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8305333 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1TDP1LMNAALOX12 | |
| SCHEMBL8308388 | 0.76 | KMO (0.62) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL15901800 | 0.75 | HTR2C (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL25780881 | 0.75 | KDM4E (0.80) | KDM4EALDH1A1TDP1LMNAALOX12 | |
| SCHEMBL13061160 | 0.75 | NR4A1 (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18731803 | 0.74 | MAPT (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8304580 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL28677807 | 0.72 | PARP1 (0.55) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31032166 | 0.72 | PARP1 (0.55) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739341-B1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | NOVARTIS AG (CH) | 1999-06-02 | — | — | EP | disclosed |