Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MET | P08581 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307187 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDMETCNR2MGAM | |
| SCHEMBL10273815 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDCNR2MGAMMAPT | |
| SCHEMBL8686194 | 0.75 | KMT2A (0.44) | ALDH1A1HPGDCNR2MGAMMAPT | |
| SCHEMBL8308456 | 0.74 | KDM4C (0.44) | ALDH1A1HPGDMAPTLMNAGAA | |
| SCHEMBL8307051 | 0.74 | MGAM (0.53) | ALDH1A1HPGDCNR2MGAMMAPT | |
| SCHEMBL14190711 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HPGDCNR2MGAMMAPT | |
| SCHEMBL8304591 | 0.73 | PPARG (0.58) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL8304592 | 0.73 | PPARG (0.58) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL8306601 | 0.71 | HIF1A (0.42) | ALDH1A1METLMNARAB9ASMN1; SMN2 | |
| SCHEMBL8306603 | 0.71 | HIF1A (0.42) | ALDH1A1METLMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |