Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 5/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322361 | 0.99 | AURKA (0.49) | F10PRSS1AURKARPS6KB1AURKB | |
| Hydrochloric Acid SCHEMBL6325502 | 0.99 | F10 (0.47) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6325892 | 0.98 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6329960 | 0.92 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| Hydrochloric Acid SCHEMBL6326766 | 0.91 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6323988 | 0.90 | CDK1 (0.45) | AURKARPS6KB1AURKBPDE5AMAPK10 | |
| SCHEMBL6326456 | 0.89 | AURKA (0.41) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6323907 | 0.88 | CDK1 (0.50) | AURKARPS6KB1AURKBPDE5AMAPK10 | |
| SCHEMBL6322321 | 0.86 | AURKA (0.42) | AURKARPS6KB1AURKBPDE5ANPC1 | |
| SCHEMBL6329487 | 0.86 | AURKA (0.43) | AURKARPS6KB1AURKBPDE5AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |