Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 6/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.49 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307208 | 0.99 | F10 (0.48) | AURKARPS6KB1AURKBF10PRSS1 | |
| Hydrochloric Acid SCHEMBL6325502 | 0.98 | F10 (0.47) | AURKARPS6KB1AURKBF10PRSS1 | |
| SCHEMBL6325892 | 0.97 | F10 (0.48) | AURKARPS6KB1AURKBF10PRSS1 | |
| SCHEMBL6329960 | 0.91 | F10 (0.48) | AURKARPS6KB1AURKBF10PRSS1 | |
| Hydrochloric Acid SCHEMBL6326766 | 0.90 | F10 (0.48) | AURKARPS6KB1AURKBF10PRSS1 | |
| SCHEMBL6323988 | 0.89 | CDK1 (0.45) | AURKARPS6KB1AURKBPDE5ACDK1 | |
| SCHEMBL6326456 | 0.88 | AURKA (0.41) | AURKARPS6KB1AURKBF10PRSS1 | |
| SCHEMBL6323907 | 0.87 | CDK1 (0.50) | AURKARPS6KB1AURKBPDE5ACDK1 | |
| SCHEMBL6322321 | 0.86 | AURKA (0.42) | AURKARPS6KB1AURKBPDE5ANPC1 | |
| SCHEMBL6329487 | 0.85 | AURKA (0.43) | AURKARPS6KB1AURKBPDE5AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | AURKA 437/4885RPS6KB1 2064/4885AURKB 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.