Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 8/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6326766 | 0.99 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6325892 | 0.92 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL8307208 | 0.92 | F10 (0.48) | F10PRSS1AURKARPS6KB1AURKB | |
| Hydrochloric Acid SCHEMBL6325502 | 0.91 | F10 (0.47) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6322361 | 0.91 | AURKA (0.49) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6323907 | 0.87 | CDK1 (0.50) | AURKARPS6KB1AURKBCNR1CNR2 | |
| SCHEMBL6329487 | 0.87 | AURKA (0.43) | AURKARPS6KB1AURKBCNR1CNR2 | |
| SCHEMBL6323988 | 0.85 | CDK1 (0.45) | AURKARPS6KB1AURKBCNR1CNR2 | |
| SCHEMBL6323093 | 0.85 | F10 (0.40) | F10PRSS1AURKARPS6KB1AURKB | |
| SCHEMBL6326456 | 0.84 | AURKA (0.41) | F10PRSS1AURKARPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | F10 11/4885PRSS1 182/4885AURKA 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.