Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665311 | 0.81 | TSHR (0.36) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL8308068 | 0.73 | CYP2C19 (0.42) | TSHRHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL19546247 | 0.73 | TSHR (0.46) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL7078250 | 0.73 | ALDH1A1 (0.42) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL8931557 | 0.71 | POLB (0.44) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL7303460 | 0.71 | TSHR (0.43) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL12807939 | 0.71 | — | — | |
| SCHEMBL8831148 | 0.71 | CTSD (0.38) | TSHRHSD17B10GAAPOLBALDH1A1 | |
| SCHEMBL19954384 | 0.71 | HTT (0.39) | TSHRHSD17B10GAAMGAMSI | |
| SCHEMBL17773453 | 0.71 | POLB (0.38) | TSHRHSD17B10GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |