Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121693 | 0.87 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL8637323 | 0.86 | TAAR1 (0.53) | LTA4HEPHX2MGLLBCHETAAR1 | |
| SCHEMBL2942858 | 0.85 | TAAR1 (0.62) | TAAR1SIGMAR1 | |
| SCHEMBL11702882 | 0.84 | TAAR1 (0.73) | LTA4HEPHX2BCHETAAR1F2 | |
| SCHEMBL8958092 | 0.83 | TAAR1 (0.65) | TAAR1 | |
| Hydrochloric Acid SCHEMBL3645890 | 0.82 | TAAR1 (0.62) | TAAR1 | |
| SCHEMBL8641804 | 0.82 | TAAR1 (0.59) | LTA4HTAAR1FFAR1 | |
| SCHEMBL12040562 | 0.80 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL12630258 | 0.80 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL9368356 | 0.79 | SIGMAR1 (0.51) | LTA4HEPHX2BCHETAAR1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |