Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679414 | 0.93 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRHPGDHTT | |
| SCHEMBL7677059 | 0.89 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRHPGDTP53 | |
| SCHEMBL8165543 | 0.89 | CASP1 (0.35) | ALDH1A1LMNAERCC5FEN1 | |
| SCHEMBL7675885 | 0.88 | ALDH1A1 (0.34) | ALDH1A1LMNATSHRHPGDTP53 | |
| SCHEMBL8177147 | 0.87 | MEN1 (0.34) | ALDH1A1FFAR1 | |
| SCHEMBL7687004 | 0.86 | ALDH1A1 (0.36) | ALDH1A1LMNATSHRHPGD | |
| SCHEMBL7683953 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDHTTUSP2 | |
| SCHEMBL7681897 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRHPGDTP53 | |
| SCHEMBL7675858 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNATSHRHPGDTP53 | |
| SCHEMBL7684617 | 0.83 | ALDH1A1 (0.34) | ALDH1A1LMNATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |