Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773853 | 0.84 | ADRA1D (0.43) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL30846758 | 0.84 | ADRA1D (0.43) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL56072 | 0.78 | MAOA (0.54) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL10520122 | 0.75 | MAPT (0.37) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL10519798 | 0.75 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL7761447 | 0.75 | MAOA (0.55) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL3834171 | 0.75 | MAOA (0.50) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL22360347 | 0.75 | SLC18A3 (0.50) | MAOAMAOBSLC6A2GRIN2BSLC18A3 | |
| SCHEMBL6787188 | 0.74 | MAOA (0.53) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL7859402 | 0.74 | MAOA (0.48) | MAOAMAOBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087124-A1 | COMPOUNDS HAVING SEROTONIN 5-HT17 RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC M4 RECEPTOR AGONIST ACTIVITY AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-14 | — | — | WO | disclosed |