Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824144 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2ERN1CYP1A2LCKFYN | |
| SCHEMBL8311611 | 0.72 | DHODH (0.34) | — | |
| SCHEMBL21585752 | 0.70 | DAO (0.37) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL17873240 | 0.68 | CYP1A2 (0.34) | SMN1; SMN2ERN1CYP1A2HSD17B10TSHR | |
| SCHEMBL19519485 | 0.66 | ALDH1A1 (0.40) | SMN1; SMN2HSD17B10TSHRALDH1A1AKR1C3 | |
| SCHEMBL978092 | 0.66 | CYP1A2 (0.35) | SMN1; SMN2ERN1CYP1A2LCKFYN | |
| SCHEMBL8310659 | 0.65 | ALDH1A1 (0.52) | SMN1; SMN2LCKFYNHSD17B10ALDH1A1 | |
| SCHEMBL8310758 | 0.65 | HSD17B10 (0.38) | SMN1; SMN2CYP1A2HSD17B10ALDH1A1MAPT | |
| SCHEMBL8307283 | 0.65 | ALDH1A1 (0.36) | SMN1; SMN2CYP1A2HSD17B10TSHRALDH1A1 | |
| SCHEMBL8308811 | 0.65 | CTNNB1 (0.34) | CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |