Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17873250 | 0.77 | UCHL1 (0.32) | CYP1A2 | |
| SCHEMBL31370988 | 0.71 | KDM4E (0.36) | ALDH1A1KDM4E | |
| SCHEMBL7325790 | 0.69 | ALDH1A1 (0.43) | HCAR2HSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL8307809 | 0.68 | SMN1; SMN2 (0.36) | CYP1A2ERN1HSD17B10TSHRMAPT | |
| SCHEMBL607237 | 0.66 | CYP1A2 (0.48) | CYP1A2ERN1TSHRALDH1A1AKR1C4 | |
| SCHEMBL2422463 | 0.66 | CASP7 (0.45) | CYP1A2ERN1HSD17B10TSHRMAPT | |
| SCHEMBL17873251 | 0.66 | XDH (0.40) | CYP1A2ERN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL29045172 | 0.65 | CYP1A2 (0.46) | CYP1A2ERN1TSHRALDH1A1AKR1C4 | |
| SCHEMBL7325775 | 0.64 | ALDH1A1 (0.41) | HSD17B10TSHRMAPTALDH1A1KDM4E | |
| SCHEMBL9868328 | 0.63 | SMN1; SMN2 (0.45) | CYP1A2ERN1HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237410-B1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2020-12-16 | — | — | EP | disclosed |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2019-04-30 | — | — | US | disclosed |
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2019-02-07 | — | — | US | disclosed |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2018-10-09 | — | — | US | disclosed |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2018-01-04 | — | — | US | disclosed |
| EP-3237410-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102482-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL5, CUL1, CUL3 | CYP1A2 41/4885ERN1 3177/4885HCAR2 3684/4885 |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL1, CRY1, CUL5 | CYP1A2 26/4885ERN1 3163/4885HCAR2 4020/4885 |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | CUL1, CRY1, CUL5 | CYP1A2 26/4885ERN1 3163/4885HCAR2 4020/4885 |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | CUL5, CUL1, CUL3 | CYP1A2 41/4885ERN1 3177/4885HCAR2 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.