Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925352 | 0.85 | HDAC6 (0.34) | HDAC6HDAC1HDAC2KCNQ4KCNQ5 | |
| SCHEMBL9171625 | 0.78 | HDAC6 (0.50) | HDAC6HDAC1HDAC2 | |
| SCHEMBL6692478 | 0.76 | HDAC6 (0.36) | HDAC6HDAC1HDAC2KCNQ4KCNQ5 | |
| SCHEMBL1207293 | 0.76 | CA14 (0.39) | HDAC6HDAC1HDAC2KCNQ4KCNQ5 | |
| SCHEMBL1743767 | 0.74 | HDAC6 (0.35) | HDAC6HDAC1HDAC2KCNQ4KCNQ5 | |
| SCHEMBL3012891 | 0.74 | HDAC6 (0.46) | HDAC6HDAC1HDAC2 | |
| SCHEMBL18756074 | 0.74 | HDAC6 (0.46) | HDAC6HDAC1HDAC2 | |
| SCHEMBL30897721 | 0.73 | HDAC6 (0.34) | HDAC6HDAC1HDAC2KCNQ4KCNQ5 | |
| SCHEMBL23752124 | 0.72 | HDAC6 (0.46) | HDAC6HDAC1HDAC2 | |
| SCHEMBL20383538 | 0.72 | HDAC6 (0.45) | HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |