Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308570 | 0.90 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL8306139 | 0.85 | TBXAS1 (0.68) | TBXAS1 | |
| SCHEMBL8309355 | 0.81 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8309655 | 0.81 | TBXAS1 (0.70) | TBXAS1 | |
| SCHEMBL8305168 | 0.79 | TBXAS1 (0.78) | TBXAS1 | |
| SCHEMBL9178744 | 0.79 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8305169 | 0.77 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL8306901 | 0.77 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8306801 | 0.77 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8304831 | 0.77 | TBXAS1 (0.74) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |