Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312961 | 0.96 | HSP90AA1 (0.46) | CHRM4DRD2HTR7HSP90AA1MEN1 | |
| SCHEMBL8311548 | 0.92 | DRD2 (0.46) | CHRM4DRD2HTR7HSP90AA1CYP3A4 | |
| SCHEMBL6988386 | 0.80 | CYP3A4 (0.44) | DRD2HSP90AA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15540339 | 0.79 | CYP19A1 (0.42) | HSP90AA1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6811167 | 0.78 | CHRM4 (0.50) | CHRM4DRD2HTR7 | |
| SCHEMBL394579 | 0.77 | MEN1 (0.54) | HSP90AA1MEN1KMT2ANPC1POLB | |
| SCHEMBL8566869 | 0.77 | HSP90AA1 (0.47) | HSP90AA1MEN1KMT2ANPC1POLB | |
| SCHEMBL23174865 | 0.77 | HCRTR1 (0.50) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL30290988 | 0.76 | IDO1 (0.58) | CHRM4DRD2HTR7MEN1KMT2A | |
| SCHEMBL4455923 | 0.76 | IDO1 (0.58) | CHRM4DRD2HTR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087124-A1 | COMPOUNDS HAVING SEROTONIN 5-HT17 RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC M4 RECEPTOR AGONIST ACTIVITY AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-14 | — | — | WO | disclosed |