Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304067 | 0.85 | LMNA (0.78) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8303960 | 0.84 | RXFP1 (0.65) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8305679 | 0.83 | RXFP1 (0.71) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8308066 | 0.82 | LMNA (0.86) | RXFP1LMNATHRBPOLBKMT2A | |
| SCHEMBL8304200 | 0.80 | MAPT (0.59) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8311946 | 0.79 | KDM4E (0.61) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8305681 | 0.79 | RXFP1 (0.66) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8305649 | 0.78 | HTT (0.61) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8311182 | 0.76 | RXFP1 (0.61) | RXFP1LMNATHRBALDH1A1XBP1 | |
| SCHEMBL8304644 | 0.75 | LMNA (0.66) | RXFP1LMNAALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |